Drug release from kollicoat SR 30D-coated nonpareil beads: Evaluation of coating level, plasticizer type, and curing condition
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چکیده
منابع مشابه
Evaluation of the effect of physical variables on in vitro release of diclofenac pellets using Box-Behnken design
Objective(s): A Box-Behnken design was used for evaluation of Eudragit coated diclofenac pellets. The purpose of this work was to optimize diclofenac pellets to improve the physicochemical properties using experimental design. Materials and Methods: Diclofenac was loaded onto the non-pareil beads using conventional coating pan. Film coating of pellets was done at the same pan. The effect of pla...
متن کاملEvaluation of the effect of physical variables on in vitro release of diclofenac pellets using Box-Behnken design
OBJECTIVES A Box-Behnken design was used for evaluation of Eudragit coated diclofenac pellets. The purpose of this work was to optimize diclofenac pellets to improve the physicochemical properties using experimental design. MATERIALS AND METHODS Diclofenac was loaded onto the non-pareil beads using conventional coating pan. Film coating of pellets was done at the same pan. The effect of plast...
متن کاملComparative Study of Aqueous Dispersion of Different Types of Polymers on Release Behavior of Salbutamol Sulphate from Coated Pellets
The present study was designed to investigate the effect of different types of coating polymers such as Eudragit RL 30D, Eudragit RS 30D, Eudragit NE 30D, Surelease, and Kollicoat SR 30D on physical properties and release pattern of salbutamol sulphate (SS) pellets which were prepared by Extrusion-Spheronization technology. All the polymers used in coating solution were in aqueous dispersion fo...
متن کاملevaluation of the effect of physical variables on in vitro release of diclofenac pellets using box-behnken design
objective(s): a box-behnken design was used for evaluation of eudragit coated diclofenac pellets. the purpose of this work was to optimize diclofenac pellets to improve the physicochemical properties using experimental design. materials and methods: diclofenac was loaded onto the non-pareil beads using conventional coating pan. film coating of pellets was done at the same pan. the effect of pla...
متن کاملMonitoring of dissolution induced changes in film coat composition by 1H NMR spectroscopy and SEM.
In our study we investigated the release mechanisms of coated oral dosage forms more deeply. The aim of the study was to monitor the buffer induced leaching out of water soluble compounds from Kollicoat SR films and to relate this process to the film properties and the release kinetics. Propranolol HCl tablets were coated with different amounts and ratios of polyvinyl acetate (Kollicoat SR) and...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2002
ISSN: 1530-9932
DOI: 10.1208/pt030215